Overview
Patient self administration
The OTS system utilizes a lozenge-on-a-handle technology, where the dosage unit is administered by rotating and dissolving it against the oral mucosal tissue. The presence of a handle on the dosage form provides a convenient, simple mechanism for the patient to self-administer drugs to the oral cavity for either transmucosal or swallowed gastrointestinal absorption, depending on the drug application.
The OTS handle makes administration convenient and noninvasive, and allows patients to easily administer the drug. Simple, yet ingenious.
Technical Notes
A convenient form for systemic delivery of drugs
The OTS product is manufactured by a direct compression process and is packaged in a convenient unit-dose blister package.
Case Study
First prescription medication approved for the treatment of breakthrough pain in opioid-tolerant cancer patients
This technology has been commercialized with fentanyl citrate as the active drug under the brand name ACTIQ® (oral transmucosal fentanyl citrate, C-II). For important information for healthcare professionals and patients, and for Prescribing Information, including the boxed warning on ACTIQ, please visit
www.actiq.com